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CRISPR/Cas9-mediated knock-in of an optimized TetO repeat for live cell imaging of endogenous loci
Nuclear organization has an important role in determining genome function; however, it is not clear how spatiotemporal organization of the genome relates to functionality. To elucidate this relationship, a method for tracking any locus of interest is desirable. Recently clustered regularly interspac...
Autores principales: | Tasan, Ipek, Sustackova, Gabriela, Zhang, Liguo, Kim, Jiah, Sivaguru, Mayandi, HamediRad, Mohammad, Wang, Yuchuan, Genova, Justin, Ma, Jian, Belmont, Andrew S, Zhao, Huimin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158506/ https://www.ncbi.nlm.nih.gov/pubmed/29912475 http://dx.doi.org/10.1093/nar/gky501 |
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