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Eukaryotic translation initiation factor 4AII contributes to microRNA-122 regulation of hepatitis C virus replication

Hepatitis C virus (HCV) is a positive sense RNA virus that persistently infects human liver, leading to cirrhosis and hepatocellular carcinoma. HCV replication requires the liver-specific microRNA-122 (miR-122). In contrast to canonical miRNA-mediated repression via 3′UTR sites, miR-122 positively r...

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Detalles Bibliográficos
Autores principales: Ahmed, Choudhary Shoaib, Winlow, Poppy L, Parsons, Aimee L, Jopling, Catherine L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158612/
https://www.ncbi.nlm.nih.gov/pubmed/29669014
http://dx.doi.org/10.1093/nar/gky262