Nucleosome conformational variability in solution and in interphase nuclei evidenced by cryo-electron microscopy of vitreous sections

In Eukaryotes, DNA is wound around the histone octamer forming the basic chromatin unit, the nucleosome. Atomic structures have been obtained from crystallography and single particle cryo-electron microscopy (cryoEM) of identical engineered particles. But native nucleosomes are dynamical entities wi...

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Detalles Bibliográficos
Autores principales: Eltsov, Mikhail, Grewe, Diana, Lemercier, Nicolas, Frangakis, Achilleas, Livolant, Françoise, Leforestier, Amélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158616/
https://www.ncbi.nlm.nih.gov/pubmed/30053160
http://dx.doi.org/10.1093/nar/gky670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158616/
https://www.ncbi.nlm.nih.gov/pubmed/30053160
http://dx.doi.org/10.1093/nar/gky670

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