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The 2B subdomain of Rep helicase links translocation along DNA with protein displacement

Helicases catalyse DNA and RNA strand separation. Proteins bound to the nucleic acid must also be displaced in order to unwind DNA. This is exemplified by accessory helicases that clear protein barriers from DNA ahead of advancing replication forks. How helicases catalyse DNA unwinding is increasing...

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Detalles Bibliográficos
Autores principales:	Brüning, Jan-Gert, Howard, Jamieson A L, Myka, Kamila K, Dillingham, Mark S, McGlynn, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158625/ https://www.ncbi.nlm.nih.gov/pubmed/30060236 http://dx.doi.org/10.1093/nar/gky673

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