Identification of a novel TIF-IA–NF-κB nucleolar stress response pathway

p53 as an effector of nucleolar stress is well defined, but p53 independent mechanisms are largely unknown. Like p53, the NF-κB transcription factor plays a critical role in maintaining cellular homeostasis under stress. Many stresses that stimulate NF-κB also disrupt nucleoli. However, the link bet...

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Detalles Bibliográficos
Autores principales: Chen, Jingyu, Lobb, Ian T, Morin, Pierre, Novo, Sonia M, Simpson, James, Kennerknecht, Kathrin, von Kriegsheim, Alex, Batchelor, Emily E, Oakley, Fiona, Stark, Lesley A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158704/
https://www.ncbi.nlm.nih.gov/pubmed/29873780
http://dx.doi.org/10.1093/nar/gky455

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