DDX49 is an RNA helicase that affects translation by regulating mRNA export and the levels of pre-ribosomal RNA

Among the proteins predicted to be a part of the DExD box RNA helicase family, the functions of DDX49 are unknown. Here, we characterize the enzymatic activities and functions of DDX49 by comparing its properties with the well-studied RNA helicase, DDX39B. We find that DDX49 exhibits a robust ATPase...

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Detalles Bibliográficos
Autores principales: Awasthi, Sharad, Verma, Mamta, Mahesh, Arun, K. Khan, Mohd Imran, Govindaraju, Gayathri, Rajavelu, Arumugam, Chavali, Pavithra L, Chavali, Sreenivas, Dhayalan, Arunkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158705/
https://www.ncbi.nlm.nih.gov/pubmed/29618122
http://dx.doi.org/10.1093/nar/gky231

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