Single-site DNA cleavage by Type III restriction endonuclease requires a site-bound enzyme and a trans-acting enzyme that are ATPase-activated

Endonucleolytic cleavage of DNA by Type III restriction-modification (RM) enzymes requires long-range communication between at least two recognition sites in inverted orientation. This results in convergence of two nuclease domains, one each from the enzymes loaded at the recognition sites with one...

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Detalles Bibliográficos
Autores principales: Ahmad, Ishtiyaq, Kulkarni, Manasi, Gopinath, Aathira, Saikrishnan, Kayarat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158743/
https://www.ncbi.nlm.nih.gov/pubmed/29846668
http://dx.doi.org/10.1093/nar/gky344

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