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Tunable order–disorder continuum in protein–DNA interactions
DNA-binding protein domains (DBDs) sample diverse conformations in equilibrium facilitating the search and recognition of specific sites on DNA over millions of energetically degenerate competing sites. We hypothesize that DBDs have co-evolved to sense and exploit the strong electric potential from...
Autores principales: | Munshi, Sneha, Gopi, Soundhararajan, Asampille, Gitanjali, Subramanian, Sandhyaa, Campos, Luis A, Atreya, Hanudatta S, Naganathan, Athi N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158747/ https://www.ncbi.nlm.nih.gov/pubmed/30107436 http://dx.doi.org/10.1093/nar/gky732 |
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