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Tunable order–disorder continuum in protein–DNA interactions

DNA-binding protein domains (DBDs) sample diverse conformations in equilibrium facilitating the search and recognition of specific sites on DNA over millions of energetically degenerate competing sites. We hypothesize that DBDs have co-evolved to sense and exploit the strong electric potential from...

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Detalles Bibliográficos
Autores principales: Munshi, Sneha, Gopi, Soundhararajan, Asampille, Gitanjali, Subramanian, Sandhyaa, Campos, Luis A, Atreya, Hanudatta S, Naganathan, Athi N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158747/
https://www.ncbi.nlm.nih.gov/pubmed/30107436
http://dx.doi.org/10.1093/nar/gky732

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