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Dynamic chromosomal tuning of a novel GAU1 lncing driver at chr12p13.32 accelerates tumorigenesis

Aberrant chromatin transformation dysregulates gene expression and may be an important driver of tumorigenesis. However, the functional role of chromosomal dynamics in tumorigenesis remains to be elucidated. Here, using in vitro and in vivo experiments, we reveal a novel long noncoding (lncing) driv...

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Detalles Bibliográficos
Autores principales:	Chai, Peiwei, Jia, Ruobing, Jia, Renbing, Pan, Hui, Wang, Shaoyun, Ni, Hongyan, Wang, Huixue, Zhou, Chuandi, Shi, Yingyun, Ge, Shengfang, Zhang, He, Fan, Xianqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158754/ https://www.ncbi.nlm.nih.gov/pubmed/29741668 http://dx.doi.org/10.1093/nar/gky366

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