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FoldX as Protein Engineering Tool: Better Than Random Based Approaches?

Improving protein stability is an important goal for basic research as well as for clinical and industrial applications but no commonly accepted and widely used strategy for efficient engineering is known. Beside random approaches like error prone PCR or physical techniques to stabilize proteins, e....

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Detalles Bibliográficos
Autores principales: Buß, Oliver, Rudat, Jens, Ochsenreither, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158775/
https://www.ncbi.nlm.nih.gov/pubmed/30275935
http://dx.doi.org/10.1016/j.csbj.2018.01.002