Prototyping a precision oncology 3.0 rapid learning platform

BACKGROUND: We describe a prototype implementation of a platform that could underlie a Precision Oncology Rapid Learning system. RESULTS: We describe the prototype platform, and examine some important issues and details. In the Appendix we provide a complete walk-through of the prototype platform. C...

Descripción completa

Detalles Bibliográficos
Autores principales: Sweetnam, Connor, Mocellin, Simone, Krauthammer, Michael, Knopf, Nathaniel, Baertsch, Robert, Shrager, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158802/
https://www.ncbi.nlm.nih.gov/pubmed/30257653
http://dx.doi.org/10.1186/s12859-018-2374-0
Descripción
Sumario:BACKGROUND: We describe a prototype implementation of a platform that could underlie a Precision Oncology Rapid Learning system. RESULTS: We describe the prototype platform, and examine some important issues and details. In the Appendix we provide a complete walk-through of the prototype platform. CONCLUSIONS: The design choices made in this implementation rest upon ten constitutive hypotheses, which, taken together, define a particular view of how a rapid learning medical platform might be defined, organized, and implemented.

Ejemplares similares