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Effects of methylprednisolone on blood-brain barrier and cerebral inflammation in cardiac surgery—a randomized trial

BACKGROUND: Cognitive dysfunction is a frequent complication to open-heart surgery. Cerebral inflammation caused by blood-brain barrier (BBB) dysfunction due to a systemic inflammatory response is considered a possible etiology. The effects of the glucocorticoid, methylprednisolone, on cerebrospinal...

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Detalles Bibliográficos
Autores principales:	Danielson, Mattias, Reinsfelt, Björn, Westerlind, Anne, Zetterberg, Henrik, Blennow, Kaj, Ricksten, Sven-Erik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158839/ https://www.ncbi.nlm.nih.gov/pubmed/30261896 http://dx.doi.org/10.1186/s12974-018-1318-y

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