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Prognosis of Hormonal Deficits in Empty Sella Syndrome Using Neuroimaging
AIM: We have evaluated the anatomic measurements on sellar area of patients who were radiologically diagnosed with empty sella to determine the relation between the amount of pressure on the adenohypophysis and hormonal imbalances. MATERIALS AND METHODS: Sixty-one cases were diagnosed with empty sel...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159034/ https://www.ncbi.nlm.nih.gov/pubmed/30283536 http://dx.doi.org/10.4103/ajns.AJNS_50_18 |
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author | Atci, Ibrahim Burak Yilmaz, Hakan Karagoz, Yesim Kocak, Ayhan |
author_facet | Atci, Ibrahim Burak Yilmaz, Hakan Karagoz, Yesim Kocak, Ayhan |
author_sort | Atci, Ibrahim Burak |
collection | PubMed |
description | AIM: We have evaluated the anatomic measurements on sellar area of patients who were radiologically diagnosed with empty sella to determine the relation between the amount of pressure on the adenohypophysis and hormonal imbalances. MATERIALS AND METHODS: Sixty-one cases were diagnosed with empty sella and had hormone tests and hypophysis magnetic resonance (MR). The cases were categorized into two groups – patients with hypophyseal hormone anomaly and patients without hormone anomaly. We have measured interclinoid distance, anteroposterior distance from the anterior diaphragm sella to the pituitary stalk, depth of the sella turcica, craniocaudal distance of the optic chiasm from the diaphragm sella, the heights of the right and left adenohypophysis, subcutaneous fat thickness measured orthogonal to the coronal suture and posteriorly at the level of C2–C3 for two groups on hypophysis and cranial MR imaging MRI. RESULTS: Twenty-five hormone-positive cases (40.9%) (hormone test were abnormal) and 36 hormone-negative cases (59.1%) (hormone tests were normal) were included in the study. The most common hormone abnormality was thyroid-stimulating hormone, T3 and T4 deficiency in 12 cases (48%) and increase in prolactin level in 7 cases (28%). Right adenohypophysis height was 1.54 ± 0.840 mm for the 1(st) group, and 1.96 ± 0.83 mm for the 2(nd) group. The left adenohypophysis height was 1.66 ± 0.80 mm for the 1(st) group, and 1.94 ± 0.94 mm for the 2(nd) group. It was found out that the thickness at right and left side in the hormone-positive group diminished significantly. CONCLUSION: Adenohypophysis height and distance between stalk and optic nerve were good determiner for hormone defect. |
format | Online Article Text |
id | pubmed-6159034 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-61590342018-10-03 Prognosis of Hormonal Deficits in Empty Sella Syndrome Using Neuroimaging Atci, Ibrahim Burak Yilmaz, Hakan Karagoz, Yesim Kocak, Ayhan Asian J Neurosurg Original Article AIM: We have evaluated the anatomic measurements on sellar area of patients who were radiologically diagnosed with empty sella to determine the relation between the amount of pressure on the adenohypophysis and hormonal imbalances. MATERIALS AND METHODS: Sixty-one cases were diagnosed with empty sella and had hormone tests and hypophysis magnetic resonance (MR). The cases were categorized into two groups – patients with hypophyseal hormone anomaly and patients without hormone anomaly. We have measured interclinoid distance, anteroposterior distance from the anterior diaphragm sella to the pituitary stalk, depth of the sella turcica, craniocaudal distance of the optic chiasm from the diaphragm sella, the heights of the right and left adenohypophysis, subcutaneous fat thickness measured orthogonal to the coronal suture and posteriorly at the level of C2–C3 for two groups on hypophysis and cranial MR imaging MRI. RESULTS: Twenty-five hormone-positive cases (40.9%) (hormone test were abnormal) and 36 hormone-negative cases (59.1%) (hormone tests were normal) were included in the study. The most common hormone abnormality was thyroid-stimulating hormone, T3 and T4 deficiency in 12 cases (48%) and increase in prolactin level in 7 cases (28%). Right adenohypophysis height was 1.54 ± 0.840 mm for the 1(st) group, and 1.96 ± 0.83 mm for the 2(nd) group. The left adenohypophysis height was 1.66 ± 0.80 mm for the 1(st) group, and 1.94 ± 0.94 mm for the 2(nd) group. It was found out that the thickness at right and left side in the hormone-positive group diminished significantly. CONCLUSION: Adenohypophysis height and distance between stalk and optic nerve were good determiner for hormone defect. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6159034/ /pubmed/30283536 http://dx.doi.org/10.4103/ajns.AJNS_50_18 Text en Copyright: © 2018 Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Atci, Ibrahim Burak Yilmaz, Hakan Karagoz, Yesim Kocak, Ayhan Prognosis of Hormonal Deficits in Empty Sella Syndrome Using Neuroimaging |
title | Prognosis of Hormonal Deficits in Empty Sella Syndrome Using Neuroimaging |
title_full | Prognosis of Hormonal Deficits in Empty Sella Syndrome Using Neuroimaging |
title_fullStr | Prognosis of Hormonal Deficits in Empty Sella Syndrome Using Neuroimaging |
title_full_unstemmed | Prognosis of Hormonal Deficits in Empty Sella Syndrome Using Neuroimaging |
title_short | Prognosis of Hormonal Deficits in Empty Sella Syndrome Using Neuroimaging |
title_sort | prognosis of hormonal deficits in empty sella syndrome using neuroimaging |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159034/ https://www.ncbi.nlm.nih.gov/pubmed/30283536 http://dx.doi.org/10.4103/ajns.AJNS_50_18 |
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