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Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome
Melanotic schwannomas (MS) are rare variants of schwannomas the occurrence of which is described in case reports only. They usually arise from posterior spinal nerve roots and less commonly from other cells of neural crest origin. Although they are relatively benign tumors in young, aggressive behav...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159093/ https://www.ncbi.nlm.nih.gov/pubmed/30283573 http://dx.doi.org/10.4103/ajns.AJNS_353_16 |
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author | Chandran, Raj Satheesh Patil, Anil Kumar Prabhakar, Rajmohan Bhanu Balachandran, Krishna |
author_facet | Chandran, Raj Satheesh Patil, Anil Kumar Prabhakar, Rajmohan Bhanu Balachandran, Krishna |
author_sort | Chandran, Raj Satheesh |
collection | PubMed |
description | Melanotic schwannomas (MS) are rare variants of schwannomas the occurrence of which is described in case reports only. They usually arise from posterior spinal nerve roots and less commonly from other cells of neural crest origin. Although they are relatively benign tumors in young, aggressive behavior is reported. They occur as isolated tumors or as part of a syndrome named Carney complex. We try to describe the pathology, diagnosis, management, and prognosis of MSs in two different cases: one cervical intramedullary with no recurrence on 5-year follow-up and the other one extramedullary in lumbar region with early recurrence and aggressive course. A brief review of literature is done. |
format | Online Article Text |
id | pubmed-6159093 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-61590932018-10-03 Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome Chandran, Raj Satheesh Patil, Anil Kumar Prabhakar, Rajmohan Bhanu Balachandran, Krishna Asian J Neurosurg Case Report Melanotic schwannomas (MS) are rare variants of schwannomas the occurrence of which is described in case reports only. They usually arise from posterior spinal nerve roots and less commonly from other cells of neural crest origin. Although they are relatively benign tumors in young, aggressive behavior is reported. They occur as isolated tumors or as part of a syndrome named Carney complex. We try to describe the pathology, diagnosis, management, and prognosis of MSs in two different cases: one cervical intramedullary with no recurrence on 5-year follow-up and the other one extramedullary in lumbar region with early recurrence and aggressive course. A brief review of literature is done. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6159093/ /pubmed/30283573 http://dx.doi.org/10.4103/ajns.AJNS_353_16 Text en Copyright: © 2018 Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Chandran, Raj Satheesh Patil, Anil Kumar Prabhakar, Rajmohan Bhanu Balachandran, Krishna Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome |
title | Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome |
title_full | Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome |
title_fullStr | Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome |
title_full_unstemmed | Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome |
title_short | Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome |
title_sort | melanotic schwannoma of spine: illustration of two cases with diverse clinical presentation and outcome |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159093/ https://www.ncbi.nlm.nih.gov/pubmed/30283573 http://dx.doi.org/10.4103/ajns.AJNS_353_16 |
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