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Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome

Melanotic schwannomas (MS) are rare variants of schwannomas the occurrence of which is described in case reports only. They usually arise from posterior spinal nerve roots and less commonly from other cells of neural crest origin. Although they are relatively benign tumors in young, aggressive behav...

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Autores principales: Chandran, Raj Satheesh, Patil, Anil Kumar, Prabhakar, Rajmohan Bhanu, Balachandran, Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159093/
https://www.ncbi.nlm.nih.gov/pubmed/30283573
http://dx.doi.org/10.4103/ajns.AJNS_353_16
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author Chandran, Raj Satheesh
Patil, Anil Kumar
Prabhakar, Rajmohan Bhanu
Balachandran, Krishna
author_facet Chandran, Raj Satheesh
Patil, Anil Kumar
Prabhakar, Rajmohan Bhanu
Balachandran, Krishna
author_sort Chandran, Raj Satheesh
collection PubMed
description Melanotic schwannomas (MS) are rare variants of schwannomas the occurrence of which is described in case reports only. They usually arise from posterior spinal nerve roots and less commonly from other cells of neural crest origin. Although they are relatively benign tumors in young, aggressive behavior is reported. They occur as isolated tumors or as part of a syndrome named Carney complex. We try to describe the pathology, diagnosis, management, and prognosis of MSs in two different cases: one cervical intramedullary with no recurrence on 5-year follow-up and the other one extramedullary in lumbar region with early recurrence and aggressive course. A brief review of literature is done.
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spelling pubmed-61590932018-10-03 Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome Chandran, Raj Satheesh Patil, Anil Kumar Prabhakar, Rajmohan Bhanu Balachandran, Krishna Asian J Neurosurg Case Report Melanotic schwannomas (MS) are rare variants of schwannomas the occurrence of which is described in case reports only. They usually arise from posterior spinal nerve roots and less commonly from other cells of neural crest origin. Although they are relatively benign tumors in young, aggressive behavior is reported. They occur as isolated tumors or as part of a syndrome named Carney complex. We try to describe the pathology, diagnosis, management, and prognosis of MSs in two different cases: one cervical intramedullary with no recurrence on 5-year follow-up and the other one extramedullary in lumbar region with early recurrence and aggressive course. A brief review of literature is done. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6159093/ /pubmed/30283573 http://dx.doi.org/10.4103/ajns.AJNS_353_16 Text en Copyright: © 2018 Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Chandran, Raj Satheesh
Patil, Anil Kumar
Prabhakar, Rajmohan Bhanu
Balachandran, Krishna
Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome
title Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome
title_full Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome
title_fullStr Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome
title_full_unstemmed Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome
title_short Melanotic Schwannoma of Spine: Illustration of Two Cases with Diverse Clinical Presentation and Outcome
title_sort melanotic schwannoma of spine: illustration of two cases with diverse clinical presentation and outcome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159093/
https://www.ncbi.nlm.nih.gov/pubmed/30283573
http://dx.doi.org/10.4103/ajns.AJNS_353_16
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