Cargando…

Abernethy malformation: beware in cases of unexplained hepatic encephalopathy in adults—case report and review of the relevant literature

The Abernethy malformation consists of a congenital extrahepatic portosystemic shunt and is believed to be extremely rare in humans. The potential implications of abnormal portovenous shunting and decreased hepatic portal flow are numerous and potentially serious. Although congenital extrahepatic po...

Descripción completa

Detalles Bibliográficos
Autores principales: Mesquita, Romeu Duarte, Sousa, Marta, Vilaverde, Filipa, Cardoso, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159114/
https://www.ncbi.nlm.nih.gov/pubmed/30363163
http://dx.doi.org/10.1259/bjrcr.20170054
Descripción
Sumario:The Abernethy malformation consists of a congenital extrahepatic portosystemic shunt and is believed to be extremely rare in humans. The potential implications of abnormal portovenous shunting and decreased hepatic portal flow are numerous and potentially serious. Although congenital extrahepatic portosystemic shunts are increasingly suspected and diagnosed in specialized centres, much of their clinical presentation and natural history is not fully understood. Symptoms of portosystemic shunt are mainly caused by increased levels of ammonia, which lead to signs of encephalopathy. Therapeutic options depend on the type of shunt and its clinical course, so the classification of the congenital portosystemic shunt is a key finding in these patients.