MRI evaluation of diffuse subcutaneous neurofibroma of the lower limb in a low resource setting

An unusual type of neurofibroma predominantly seen in children and young adults is diffuse neurofibroma. We present a 25-year-old female with recurring soft tissue masses in her right lower limb. MRI showed areas of T(1) iso-intensity and T(2) hyperintensity relative to skeletal muscle within the su...

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Detalles Bibliográficos
Autores principales: Adeniji-Sofoluwe, Adenike Temitayo, Ogunleye, Olanrewaju Adebusuyi, Okolo, Clement Abu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159117/
https://www.ncbi.nlm.nih.gov/pubmed/30363148
http://dx.doi.org/10.1259/bjrcr.20170090
Descripción
Sumario:An unusual type of neurofibroma predominantly seen in children and young adults is diffuse neurofibroma. We present a 25-year-old female with recurring soft tissue masses in her right lower limb. MRI showed areas of T(1) iso-intensity and T(2) hyperintensity relative to skeletal muscle within the subcutaneous fat. These masses show marked enhancement post gadolinium administration. Histological examination of the excised mass showed diffuse neurofibroma. The rare nature of this tumour and the limited literature describing the imaging features make the diagnosis relatively difficult for a radiologist.

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