Loss of intratumoral macroscopic fat in renal angiomyolipoma following chemoradiation therapy for pancreatic cancer

Angiomyolipoma (AML) is the most common benign mesenchymal tumour of the kidney. Classically, AML can readily be diagnosed by identifying the negatively attenuating intratumoral macroscopic fat component on non-enhanced CT scans. However, intratumoral macroscopic fat may not be visible on CT scans,...

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Autores principales: Miller, Frank Howard, Minocha, Jeet, Parthasarathy, Sudharshan, Adam, Sharon Zahava, Parada, Carolina, Yaghmai, Vahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159275/
https://www.ncbi.nlm.nih.gov/pubmed/30363307
http://dx.doi.org/10.1259/bjrcr.20150439
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author Miller, Frank Howard
Minocha, Jeet
Parthasarathy, Sudharshan
Adam, Sharon Zahava
Parada, Carolina
Yaghmai, Vahid
author_facet Miller, Frank Howard
Minocha, Jeet
Parthasarathy, Sudharshan
Adam, Sharon Zahava
Parada, Carolina
Yaghmai, Vahid
author_sort Miller, Frank Howard
collection PubMed
description Angiomyolipoma (AML) is the most common benign mesenchymal tumour of the kidney. Classically, AML can readily be diagnosed by identifying the negatively attenuating intratumoral macroscopic fat component on non-enhanced CT scans. However, intratumoral macroscopic fat may not be visible on CT scans, mimicking renal cell carcinoma. We report a case of renal AML with CT scan evidence of macroscopic intratumoral fat that was not readily visible on subsequent CT or MRI, presumably owing to a generalized rapid loss of adipose tissue due to cachexia in a patient with pancreatic adenocarcinoma. Radiologists should be aware that AML may lose its intratumoral fat on follow-up imaging and may simulate renal cell carcinoma.
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spelling pubmed-61592752018-10-25 Loss of intratumoral macroscopic fat in renal angiomyolipoma following chemoradiation therapy for pancreatic cancer Miller, Frank Howard Minocha, Jeet Parthasarathy, Sudharshan Adam, Sharon Zahava Parada, Carolina Yaghmai, Vahid BJR Case Rep Case Report Angiomyolipoma (AML) is the most common benign mesenchymal tumour of the kidney. Classically, AML can readily be diagnosed by identifying the negatively attenuating intratumoral macroscopic fat component on non-enhanced CT scans. However, intratumoral macroscopic fat may not be visible on CT scans, mimicking renal cell carcinoma. We report a case of renal AML with CT scan evidence of macroscopic intratumoral fat that was not readily visible on subsequent CT or MRI, presumably owing to a generalized rapid loss of adipose tissue due to cachexia in a patient with pancreatic adenocarcinoma. Radiologists should be aware that AML may lose its intratumoral fat on follow-up imaging and may simulate renal cell carcinoma. The British Institute of Radiology 2016-10-14 /pmc/articles/PMC6159275/ /pubmed/30363307 http://dx.doi.org/10.1259/bjrcr.20150439 Text en © 2016 The Authors. Published by the British Institute of Radiology http://creativecommons.org/licenses/by/4.0/ This is an open access article under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Miller, Frank Howard
Minocha, Jeet
Parthasarathy, Sudharshan
Adam, Sharon Zahava
Parada, Carolina
Yaghmai, Vahid
Loss of intratumoral macroscopic fat in renal angiomyolipoma following chemoradiation therapy for pancreatic cancer
title Loss of intratumoral macroscopic fat in renal angiomyolipoma following chemoradiation therapy for pancreatic cancer
title_full Loss of intratumoral macroscopic fat in renal angiomyolipoma following chemoradiation therapy for pancreatic cancer
title_fullStr Loss of intratumoral macroscopic fat in renal angiomyolipoma following chemoradiation therapy for pancreatic cancer
title_full_unstemmed Loss of intratumoral macroscopic fat in renal angiomyolipoma following chemoradiation therapy for pancreatic cancer
title_short Loss of intratumoral macroscopic fat in renal angiomyolipoma following chemoradiation therapy for pancreatic cancer
title_sort loss of intratumoral macroscopic fat in renal angiomyolipoma following chemoradiation therapy for pancreatic cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159275/
https://www.ncbi.nlm.nih.gov/pubmed/30363307
http://dx.doi.org/10.1259/bjrcr.20150439
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