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Live-Cell Imaging and Functional Dissection of Xist RNA Reveal Mechanisms of X Chromosome Inactivation and Reactivation

We double-tagged Xist (inactivated X chromosome-specific transcript), a prototype long non-coding RNA pivotal for X chromosome inactivation (XCI), using the programmable RNA sequence binding domain of Pumilio protein, one tag for live-cell imaging and the other replacing A-repeat (a critical domain...

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Detalles Bibliográficos
Autores principales:	Ha, Norbert, Lai, Lan-Tian, Chelliah, Rosi, Zhen, Yashu, Yi Vanessa, Seet Pei, Lai, Soak-Kuan, Li, Hoi-Yeung, Ludwig, Alexander, Sandin, Sara, Chen, Lingyi, Zhang, Li-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159346/ https://www.ncbi.nlm.nih.gov/pubmed/30266032 http://dx.doi.org/10.1016/j.isci.2018.09.007

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