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Bacterial EndoMS/NucS acts as a clamp-mediated mismatch endonuclease to prevent asymmetric accumulation of replication errors

Mismatch repair (MMR) systems based on MutS eliminate mismatches originating from replication errors. Despite extensive conservation of mutS homologues throughout the three domains of life, Actinobacteria and some archaea do not have genes homologous to mutS. Here, we report that EndoMS/NucS of Cory...

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Detalles Bibliográficos
Autores principales: Takemoto, Norihiko, Numata, Itaru, Su’etsugu, Masayuki, Miyoshi-Akiyama, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159521/
https://www.ncbi.nlm.nih.gov/pubmed/29878158
http://dx.doi.org/10.1093/nar/gky481