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Atomic Force Microscopy Analysis of EPPS-Driven Degradation and Reformation of Amyloid-β Aggregates

Amyloid-β (Aβ) peptides can be aggregated into β-sheet rich fibrils or plaques and deposited on the extracellular matrix of brain tissues, which is a hallmark of Alzheimer’s disease. Several drug candidates have been designed to retard the progression of the neurodegenerative disorder or to eliminat...

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Detalles Bibliográficos
Autores principales: Lee, Wonseok, Lee, Sang Won, Lee, Gyudo, Yoon, Dae Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159726/
https://www.ncbi.nlm.nih.gov/pubmed/30480247
http://dx.doi.org/10.3233/ADR-170024

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