Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

BACKGROUND. Understanding the integrated immunogenomic landscape of advanced prostate cancer (APC) could impact stratified treatment selection. METHODS. Defective mismatch repair (dMMR) status was determined by either loss of mismatch repair protein expression on IHC or microsatellite instability (M...

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Detalles Bibliográficos
Autores principales: Nava Rodrigues, Daniel, Rescigno, Pasquale, Liu, David, Yuan, Wei, Carreira, Suzanne, Lambros, Maryou B., Seed, George, Mateo, Joaquin, Riisnaes, Ruth, Mullane, Stephanie, Margolis, Claire, Miao, Diana, Miranda, Susana, Dolling, David, Clarke, Matthew, Bertan, Claudia, Crespo, Mateus, Boysen, Gunther, Ferreira, Ana, Sharp, Adam, Figueiredo, Ines, Keliher, Daniel, Aldubayan, Saud, Burke, Kelly P., Sumanasuriya, Semini, Fontes, Mariane Sousa, Bianchini, Diletta, Zafeiriou, Zafeiris, Teixeira Mendes, Larissa Sena, Mouw, Kent, Schweizer, Michael T., Pritchard, Colin C., Salipante, Stephen, Taplin, Mary-Ellen, Beltran, Himisha, Rubin, Mark A., Cieslik, Marcin, Robinson, Dan, Heath, Elizabeth, Schultz, Nikolaus, Armenia, Joshua, Abida, Wassim, Scher, Howard, Lord, Christopher, D’Andrea, Alan, Sawyers, Charles L., Chinnaiyan, Arul M., Alimonti, Andrea, Nelson, Peter S., Drake, Charles G., Van Allen, Eliezer M., de Bono, Johann S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2018
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159966/
https://www.ncbi.nlm.nih.gov/pubmed/30179225
http://dx.doi.org/10.1172/JCI121924

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