Efficacy of pyrazinoic acid dry powder aerosols in resolving necrotic and non-necrotic granulomas in a guinea pig model of tuberculosis

New therapeutic strategies are needed to treat drug resistant tuberculosis (TB) and to improve treatment for drug sensitive TB. Pyrazinamide (PZA) is a critical component of current first-line TB therapy. However, the rise in PZA-resistant TB cases jeopardizes the future utility of PZA. To address t...

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Detalles Bibliográficos
Autores principales: Montgomery, Stephanie A., Young, Ellen F., Durham, Phillip G., Zulauf, Katelyn E., Rank, Laura, Miller, Brittany K., Hayden, Jennifer D., Lin, Feng-Chang, Welch, John T., Hickey, Anthony J., Braunstein, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160074/
https://www.ncbi.nlm.nih.gov/pubmed/30261007
http://dx.doi.org/10.1371/journal.pone.0204495

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