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Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases
Paragangliomas are neuro-endocrine tumors originating from the adrenal gland. They are usually benign and nonfunctioning, rarely seen in central nervous system. More than 90% of central nervous system paragangliomas are manifested as carotid and glomus jugulare tumors. Spinal paragangliomas are quit...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160075/ https://www.ncbi.nlm.nih.gov/pubmed/30235741 http://dx.doi.org/10.1097/MD.0000000000012468 |
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author | Turk, Okan Yaldiz, Can Antar, Veysel Batur, Sebnem Demirel, Nail Atci, Burak Özdemir, Nuriye Güzin Koçak, Ayhan |
author_facet | Turk, Okan Yaldiz, Can Antar, Veysel Batur, Sebnem Demirel, Nail Atci, Burak Özdemir, Nuriye Güzin Koçak, Ayhan |
author_sort | Turk, Okan |
collection | PubMed |
description | Paragangliomas are neuro-endocrine tumors originating from the adrenal gland. They are usually benign and nonfunctioning, rarely seen in central nervous system. More than 90% of central nervous system paragangliomas are manifested as carotid and glomus jugulare tumors. Spinal paragangliomas are quite rare. The study was conducted through retrospective analysis of the files of the patients who had undergone surgery with pre-diagnosis of spinal intradural tumor between 2011 and 2017 and diagnosed with paraganglioma. A total of 8 patients (4 females and 4 males) were included in the study. Mean age of the patients was 51.1 years (28–64). Time to admission was mean 6.5 months (3 weeks–24 months). Recurrence was not observed in 7 patients, 1 patient is being followed up due to residual tumor. Treatment may be achieved through recognizing malignant transformation in patients who were not diagnosed histopathologically. We consider that quality of life of the patients may be improved through this way. |
format | Online Article Text |
id | pubmed-6160075 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-61600752018-10-12 Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases Turk, Okan Yaldiz, Can Antar, Veysel Batur, Sebnem Demirel, Nail Atci, Burak Özdemir, Nuriye Güzin Koçak, Ayhan Medicine (Baltimore) Research Article Paragangliomas are neuro-endocrine tumors originating from the adrenal gland. They are usually benign and nonfunctioning, rarely seen in central nervous system. More than 90% of central nervous system paragangliomas are manifested as carotid and glomus jugulare tumors. Spinal paragangliomas are quite rare. The study was conducted through retrospective analysis of the files of the patients who had undergone surgery with pre-diagnosis of spinal intradural tumor between 2011 and 2017 and diagnosed with paraganglioma. A total of 8 patients (4 females and 4 males) were included in the study. Mean age of the patients was 51.1 years (28–64). Time to admission was mean 6.5 months (3 weeks–24 months). Recurrence was not observed in 7 patients, 1 patient is being followed up due to residual tumor. Treatment may be achieved through recognizing malignant transformation in patients who were not diagnosed histopathologically. We consider that quality of life of the patients may be improved through this way. Wolters Kluwer Health 2018-09-21 /pmc/articles/PMC6160075/ /pubmed/30235741 http://dx.doi.org/10.1097/MD.0000000000012468 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | Research Article Turk, Okan Yaldiz, Can Antar, Veysel Batur, Sebnem Demirel, Nail Atci, Burak Özdemir, Nuriye Güzin Koçak, Ayhan Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases |
title | Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases |
title_full | Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases |
title_fullStr | Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases |
title_full_unstemmed | Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases |
title_short | Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases |
title_sort | spinal paragangliomas: surgical treatment and follow-up outcomes in eight cases |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160075/ https://www.ncbi.nlm.nih.gov/pubmed/30235741 http://dx.doi.org/10.1097/MD.0000000000012468 |
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