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Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases

Paragangliomas are neuro-endocrine tumors originating from the adrenal gland. They are usually benign and nonfunctioning, rarely seen in central nervous system. More than 90% of central nervous system paragangliomas are manifested as carotid and glomus jugulare tumors. Spinal paragangliomas are quit...

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Autores principales: Turk, Okan, Yaldiz, Can, Antar, Veysel, Batur, Sebnem, Demirel, Nail, Atci, Burak, Özdemir, Nuriye Güzin, Koçak, Ayhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160075/
https://www.ncbi.nlm.nih.gov/pubmed/30235741
http://dx.doi.org/10.1097/MD.0000000000012468
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author Turk, Okan
Yaldiz, Can
Antar, Veysel
Batur, Sebnem
Demirel, Nail
Atci, Burak
Özdemir, Nuriye Güzin
Koçak, Ayhan
author_facet Turk, Okan
Yaldiz, Can
Antar, Veysel
Batur, Sebnem
Demirel, Nail
Atci, Burak
Özdemir, Nuriye Güzin
Koçak, Ayhan
author_sort Turk, Okan
collection PubMed
description Paragangliomas are neuro-endocrine tumors originating from the adrenal gland. They are usually benign and nonfunctioning, rarely seen in central nervous system. More than 90% of central nervous system paragangliomas are manifested as carotid and glomus jugulare tumors. Spinal paragangliomas are quite rare. The study was conducted through retrospective analysis of the files of the patients who had undergone surgery with pre-diagnosis of spinal intradural tumor between 2011 and 2017 and diagnosed with paraganglioma. A total of 8 patients (4 females and 4 males) were included in the study. Mean age of the patients was 51.1 years (28–64). Time to admission was mean 6.5 months (3 weeks–24 months). Recurrence was not observed in 7 patients, 1 patient is being followed up due to residual tumor. Treatment may be achieved through recognizing malignant transformation in patients who were not diagnosed histopathologically. We consider that quality of life of the patients may be improved through this way.
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spelling pubmed-61600752018-10-12 Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases Turk, Okan Yaldiz, Can Antar, Veysel Batur, Sebnem Demirel, Nail Atci, Burak Özdemir, Nuriye Güzin Koçak, Ayhan Medicine (Baltimore) Research Article Paragangliomas are neuro-endocrine tumors originating from the adrenal gland. They are usually benign and nonfunctioning, rarely seen in central nervous system. More than 90% of central nervous system paragangliomas are manifested as carotid and glomus jugulare tumors. Spinal paragangliomas are quite rare. The study was conducted through retrospective analysis of the files of the patients who had undergone surgery with pre-diagnosis of spinal intradural tumor between 2011 and 2017 and diagnosed with paraganglioma. A total of 8 patients (4 females and 4 males) were included in the study. Mean age of the patients was 51.1 years (28–64). Time to admission was mean 6.5 months (3 weeks–24 months). Recurrence was not observed in 7 patients, 1 patient is being followed up due to residual tumor. Treatment may be achieved through recognizing malignant transformation in patients who were not diagnosed histopathologically. We consider that quality of life of the patients may be improved through this way. Wolters Kluwer Health 2018-09-21 /pmc/articles/PMC6160075/ /pubmed/30235741 http://dx.doi.org/10.1097/MD.0000000000012468 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle Research Article
Turk, Okan
Yaldiz, Can
Antar, Veysel
Batur, Sebnem
Demirel, Nail
Atci, Burak
Özdemir, Nuriye Güzin
Koçak, Ayhan
Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases
title Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases
title_full Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases
title_fullStr Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases
title_full_unstemmed Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases
title_short Spinal paragangliomas: Surgical treatment and follow-up outcomes in eight cases
title_sort spinal paragangliomas: surgical treatment and follow-up outcomes in eight cases
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160075/
https://www.ncbi.nlm.nih.gov/pubmed/30235741
http://dx.doi.org/10.1097/MD.0000000000012468
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