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Novel histone deacetylase inhibitors and embryo aggregation enhance cloned embryo development and ES cell derivation in pigs

The histone deacetylase inhibitor (HDACi) has been investigated for treating cancers and many other diseases as well as enhancing the reprogramming efficiency in cloned embryos for decades. In the present study, we investigated the effects of two novel HDAC inhibitors, i.e., HDACi-14 and -79, at the...

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Detalles Bibliográficos
Autores principales: Siriboon, Chawalit, Li, Tzai-Shiuan, Yu, Chao-Wu, Chern, Ji-Wang, Ju, Jyh-Cherng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160101/
https://www.ncbi.nlm.nih.gov/pubmed/30261020
http://dx.doi.org/10.1371/journal.pone.0204588

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