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Evaluation of willingness to pay per quality-adjusted life year for a cure: A contingent valuation method using a scenario-based survey

Cost-effectiveness is 1 of the most important factors in medicine reimbursement, and social willingness to pay (WTP) can provide evidence for the threshold of cost-effectiveness analysis. Recently, the concept of curative medicines has been introduced, so it is necessary to study their cost-effectiv...

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Autores principales: Song, Hyun Jin, Lee, Eui-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160178/
https://www.ncbi.nlm.nih.gov/pubmed/30235732
http://dx.doi.org/10.1097/MD.0000000000012453
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author Song, Hyun Jin
Lee, Eui-Kyung
author_facet Song, Hyun Jin
Lee, Eui-Kyung
author_sort Song, Hyun Jin
collection PubMed
description Cost-effectiveness is 1 of the most important factors in medicine reimbursement, and social willingness to pay (WTP) can provide evidence for the threshold of cost-effectiveness analysis. Recently, the concept of curative medicines has been introduced, so it is necessary to study their cost-effectiveness. This study aimed to estimate WTP per quality-adjusted life year (QALY) for a cure in the Korean general population. A total of 507 people from the general population, proportionally assigned by sex, age, and region, participated in face-to-face interviews. The contingent valuation survey was conducted with scenarios involving 4 EuroQol-5 dimensions (EQ-5D) with different health statuses. We assumed a treatment that moved the health status of each scenario to perfect health. WTP for 1 year of treatment was derived using a double-bounded format followed by open-ended answers. In the cure scenario, the post-treatment effect continued for a lifetime; in the non-cure scenario, the effect instantly stopped when treatment was terminated. Additionally, prolonged treatment effects lasting 5 and 10 years were added. To identify the factors influencing WTP, a multi-level analysis was performed. WTP per QALY for the non-cure scenario was KRW 15 million/QALY. For the cure scenario, WTP was 2.3 times higher (KRW 35 million/QALY) than in the non-cure scenario. The results for the prolonged treatment effect scenarios were KRW 22 million/QALY and KRW 27 million/QALY, which are 1.4 and 1.8 times higher than the non-cure scenario, respectively. In all scenarios, the statistically significant factors affecting WTP per QALY were higher education, higher household income, and healthcare provider. This study revealed that WTP for a cure treatment was higher than that for non-cure; this higher WTP should be considered in future decision-making regarding curative treatments.
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spelling pubmed-61601782018-10-12 Evaluation of willingness to pay per quality-adjusted life year for a cure: A contingent valuation method using a scenario-based survey Song, Hyun Jin Lee, Eui-Kyung Medicine (Baltimore) Research Article Cost-effectiveness is 1 of the most important factors in medicine reimbursement, and social willingness to pay (WTP) can provide evidence for the threshold of cost-effectiveness analysis. Recently, the concept of curative medicines has been introduced, so it is necessary to study their cost-effectiveness. This study aimed to estimate WTP per quality-adjusted life year (QALY) for a cure in the Korean general population. A total of 507 people from the general population, proportionally assigned by sex, age, and region, participated in face-to-face interviews. The contingent valuation survey was conducted with scenarios involving 4 EuroQol-5 dimensions (EQ-5D) with different health statuses. We assumed a treatment that moved the health status of each scenario to perfect health. WTP for 1 year of treatment was derived using a double-bounded format followed by open-ended answers. In the cure scenario, the post-treatment effect continued for a lifetime; in the non-cure scenario, the effect instantly stopped when treatment was terminated. Additionally, prolonged treatment effects lasting 5 and 10 years were added. To identify the factors influencing WTP, a multi-level analysis was performed. WTP per QALY for the non-cure scenario was KRW 15 million/QALY. For the cure scenario, WTP was 2.3 times higher (KRW 35 million/QALY) than in the non-cure scenario. The results for the prolonged treatment effect scenarios were KRW 22 million/QALY and KRW 27 million/QALY, which are 1.4 and 1.8 times higher than the non-cure scenario, respectively. In all scenarios, the statistically significant factors affecting WTP per QALY were higher education, higher household income, and healthcare provider. This study revealed that WTP for a cure treatment was higher than that for non-cure; this higher WTP should be considered in future decision-making regarding curative treatments. Wolters Kluwer Health 2018-09-21 /pmc/articles/PMC6160178/ /pubmed/30235732 http://dx.doi.org/10.1097/MD.0000000000012453 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle Research Article
Song, Hyun Jin
Lee, Eui-Kyung
Evaluation of willingness to pay per quality-adjusted life year for a cure: A contingent valuation method using a scenario-based survey
title Evaluation of willingness to pay per quality-adjusted life year for a cure: A contingent valuation method using a scenario-based survey
title_full Evaluation of willingness to pay per quality-adjusted life year for a cure: A contingent valuation method using a scenario-based survey
title_fullStr Evaluation of willingness to pay per quality-adjusted life year for a cure: A contingent valuation method using a scenario-based survey
title_full_unstemmed Evaluation of willingness to pay per quality-adjusted life year for a cure: A contingent valuation method using a scenario-based survey
title_short Evaluation of willingness to pay per quality-adjusted life year for a cure: A contingent valuation method using a scenario-based survey
title_sort evaluation of willingness to pay per quality-adjusted life year for a cure: a contingent valuation method using a scenario-based survey
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160178/
https://www.ncbi.nlm.nih.gov/pubmed/30235732
http://dx.doi.org/10.1097/MD.0000000000012453
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