Comparative study of esketamine and racemic ketamine in treatment-resistant depression: Protocol for a non-inferiority clinical trial

INTRODUCTION: The use of ketamine as an option in the treatment of depressive disorder is growing rapidly, supported by numerous clinical trials attesting its efficacy and safety. Esketamine, the S (+) enantiomer of ketamine, is the most widely used form in the anesthetic environment in some countri...

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Detalles Bibliográficos
Autores principales: Correia-Melo, Fernanda S., Leal, Gustavo C., Carvalho, Michelle S., Jesus-Nunes, Ana Paula, Ferreira, Carolina B.N., Vieira, Flávia, Magnavita, Guilherme, Vale, Lucas A.S., Mello, Rodrigo P., Nakahira, Carolina, Argolo, Felipe C., Cardoso, Tanise, Souza, Cezar D.S., Fontes, Ana Teresa C., Ferreira, Marcelo B., Araújo-de-Freitas, Lucas, Tuena, Marco A., Echegaray, Mariana V.F., Cavalcanti, Diogo E., Lucchese, Ana C., Bandeira, Igor D., Telles, Manuela, Lima, Cássio S., Sampaio, Aline S., Silva, Samantha S., Marback, Roberta F., Del-Porto, José A., Abreu, José Neander, Sarin, Luciana M., Paixão, Camilla S., Carvalho, Lucas P., Machado, Paulo R.L., Turecki, Gustavo, Lacerda, Acioly L.T., Quarantini, Lucas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160185/
https://www.ncbi.nlm.nih.gov/pubmed/30235716
http://dx.doi.org/10.1097/MD.0000000000012414

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