Norepinephrine stimulates glycogenolysis in astrocytes to fuel neurons with lactate

The mechanism of rapid energy supply to the brain, especially to accommodate the heightened metabolic activity of excited states, is not well-understood. We explored the role of glycogen as a fuel source for neuromodulation using the noradrenergic stimulation of glia in a computational model of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Coggan, Jay S., Keller, Daniel, Calì, Corrado, Lehväslaiho, Heikki, Markram, Henry, Schürmann, Felix, Magistretti, Pierre J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160207/
https://www.ncbi.nlm.nih.gov/pubmed/30161133
http://dx.doi.org/10.1371/journal.pcbi.1006392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160207/
https://www.ncbi.nlm.nih.gov/pubmed/30161133
http://dx.doi.org/10.1371/journal.pcbi.1006392

Ejemplares similares