Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus

Hepatitis E virus (HEV) is one of the leading causes of acute viral hepatitis. It also causes acute liver failure and acute-on-chronic liver failure in many patients, such as those suffering from other infections/liver injuries or organ transplant/chemotherapy recipients. Despite widespread sporadic...

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Detalles Bibliográficos
Autores principales: Anang, Saumya, Kaushik, Nidhi, Surjit, Milan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160310/
https://www.ncbi.nlm.nih.gov/pubmed/30271744
http://dx.doi.org/10.14218/JCTH.2018.00005
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author Anang, Saumya
Kaushik, Nidhi
Surjit, Milan
author_facet Anang, Saumya
Kaushik, Nidhi
Surjit, Milan
author_sort Anang, Saumya
collection PubMed
description Hepatitis E virus (HEV) is one of the leading causes of acute viral hepatitis. It also causes acute liver failure and acute-on-chronic liver failure in many patients, such as those suffering from other infections/liver injuries or organ transplant/chemotherapy recipients. Despite widespread sporadic and epidemic incidents, there is no specific treatment against HEV, justifying an urgent need for developing a potent antiviral against it. This review summarizes the known antiviral candidates and provides an overview of the potential targets for the development of specific antivirals against HEV.
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spelling pubmed-61603102018-09-28 Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus Anang, Saumya Kaushik, Nidhi Surjit, Milan J Clin Transl Hepatol Review Article Hepatitis E virus (HEV) is one of the leading causes of acute viral hepatitis. It also causes acute liver failure and acute-on-chronic liver failure in many patients, such as those suffering from other infections/liver injuries or organ transplant/chemotherapy recipients. Despite widespread sporadic and epidemic incidents, there is no specific treatment against HEV, justifying an urgent need for developing a potent antiviral against it. This review summarizes the known antiviral candidates and provides an overview of the potential targets for the development of specific antivirals against HEV. XIA & HE Publishing Inc. 2018-06-28 2018-09-28 /pmc/articles/PMC6160310/ /pubmed/30271744 http://dx.doi.org/10.14218/JCTH.2018.00005 Text en © 2018 Authors. http://creativecommons.org/licenses/by-nc/4.0/ This article has been published under the terms of Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0), which permits noncommercial unrestricted use, distribution, and reproduction in any medium, provided that the following statement is provided. “This article has been published in Journal of Clinical and Translational Hepatology at DOI: 10.14218/JCTH.2018.00005 and can also be viewed on the Journal’s website at http://www.jcthnet.com”.
spellingShingle Review Article
Anang, Saumya
Kaushik, Nidhi
Surjit, Milan
Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus
title Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus
title_full Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus
title_fullStr Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus
title_full_unstemmed Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus
title_short Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus
title_sort recent advances towards the development of a potent antiviral against the hepatitis e virus
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160310/
https://www.ncbi.nlm.nih.gov/pubmed/30271744
http://dx.doi.org/10.14218/JCTH.2018.00005
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