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Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus
Hepatitis E virus (HEV) is one of the leading causes of acute viral hepatitis. It also causes acute liver failure and acute-on-chronic liver failure in many patients, such as those suffering from other infections/liver injuries or organ transplant/chemotherapy recipients. Despite widespread sporadic...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
XIA & HE Publishing Inc.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160310/ https://www.ncbi.nlm.nih.gov/pubmed/30271744 http://dx.doi.org/10.14218/JCTH.2018.00005 |
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author | Anang, Saumya Kaushik, Nidhi Surjit, Milan |
author_facet | Anang, Saumya Kaushik, Nidhi Surjit, Milan |
author_sort | Anang, Saumya |
collection | PubMed |
description | Hepatitis E virus (HEV) is one of the leading causes of acute viral hepatitis. It also causes acute liver failure and acute-on-chronic liver failure in many patients, such as those suffering from other infections/liver injuries or organ transplant/chemotherapy recipients. Despite widespread sporadic and epidemic incidents, there is no specific treatment against HEV, justifying an urgent need for developing a potent antiviral against it. This review summarizes the known antiviral candidates and provides an overview of the potential targets for the development of specific antivirals against HEV. |
format | Online Article Text |
id | pubmed-6160310 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | XIA & HE Publishing Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-61603102018-09-28 Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus Anang, Saumya Kaushik, Nidhi Surjit, Milan J Clin Transl Hepatol Review Article Hepatitis E virus (HEV) is one of the leading causes of acute viral hepatitis. It also causes acute liver failure and acute-on-chronic liver failure in many patients, such as those suffering from other infections/liver injuries or organ transplant/chemotherapy recipients. Despite widespread sporadic and epidemic incidents, there is no specific treatment against HEV, justifying an urgent need for developing a potent antiviral against it. This review summarizes the known antiviral candidates and provides an overview of the potential targets for the development of specific antivirals against HEV. XIA & HE Publishing Inc. 2018-06-28 2018-09-28 /pmc/articles/PMC6160310/ /pubmed/30271744 http://dx.doi.org/10.14218/JCTH.2018.00005 Text en © 2018 Authors. http://creativecommons.org/licenses/by-nc/4.0/ This article has been published under the terms of Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0), which permits noncommercial unrestricted use, distribution, and reproduction in any medium, provided that the following statement is provided. “This article has been published in Journal of Clinical and Translational Hepatology at DOI: 10.14218/JCTH.2018.00005 and can also be viewed on the Journal’s website at http://www.jcthnet.com”. |
spellingShingle | Review Article Anang, Saumya Kaushik, Nidhi Surjit, Milan Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus |
title | Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus |
title_full | Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus |
title_fullStr | Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus |
title_full_unstemmed | Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus |
title_short | Recent Advances Towards the Development of a Potent Antiviral Against the Hepatitis E Virus |
title_sort | recent advances towards the development of a potent antiviral against the hepatitis e virus |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160310/ https://www.ncbi.nlm.nih.gov/pubmed/30271744 http://dx.doi.org/10.14218/JCTH.2018.00005 |
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