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Timing and mechanism of conceptus demise in a complement regulatory membrane protein deficient mouse

PROBLEM: Crry is a widely expressed type 1 transmembrane complement regulatory protein in rodents which protects self‐tissue by downregulating C3 activation. Crry (−/−) concepti produced by Crry (+/−) × Crry (+/−) matings are attacked by maternal complement system leading to loss before day 10. The...

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Detalles Bibliográficos
Autores principales:	Triebwasser, Michael P., Wu, Xiaobo, Bertram, Paula, Hourcade, Dennis E., Nelson, Donald Michael, Atkinson, John P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Immunological Factors in Pregnancy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160323/ https://www.ncbi.nlm.nih.gov/pubmed/29924462 http://dx.doi.org/10.1111/aji.12997

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