Cargando…

SCF(β-TRCP) E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation

Wnt signaling has emerged as a major regulator of tissue development by governing the self-renewal and maintenance of stem cells in most tissue types. As a key upstream regulator of the Wnt pathway, the transmembrane E3 ligase ZNRF3 has recently been established to play a role in negative regulation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ci, Yanpeng, Li, Xiaoning, Chen, Maorong, Zhong, Jiateng, North, Brian J., Inuzuka, Hiroyuki, He, Xi, Li, Yu, Guo, Jianping, Dai, Xiangpeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Higher Education Press 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160385/ https://www.ncbi.nlm.nih.gov/pubmed/29497989 http://dx.doi.org/10.1007/s13238-018-0510-2

Ejemplares similares

SCF(β-TRCP) regulates osteoclastogenesis via promoting CYLD ubiquitination
por: Wu, Xiaomian, et al.
Publicado: (2014)

Cullin 3(SPOP) ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6
por: Tan, Yuyong, et al.
Publicado: (2017)

SCF(β-TRCP) targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration
por: Zhong, Jiateng, et al.
Publicado: (2013)

SCF(β-TRCP) promotes cell growth by targeting PR-Set7/Set8 for degradation
por: Wang, Zhiwei, et al.
Publicado: (2015)

SCFβ‐TrCP ubiquitinates CHK1 in an AMPK‐dependent manner in response to glucose deprivation
por: Ma, Ying, et al.
Publicado: (2018)

Datasets from an interaction proteomics screen for substrates of the SCF(βTrCP) ubiquitin ligase
por: Magliozzi, Roberto, et al.
Publicado: (2015)

The ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation
por: Lee, Chih-Yuan, et al.
Publicado: (2017)

Serine Phosphorylation by mTORC1 Promotes IRS-1 Degradation through SCFβ-TRCP E3 Ubiquitin Ligase
por: Yoneyama, Yosuke, et al.
Publicado: (2018)

Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin
por: Zebisch, Matthias, et al.
Publicado: (2013)

SCF(β-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2
por: Shaik, Shavali, et al.
Publicado: (2012)

Regulation of Postsynaptic RapGAP SPAR by Polo-like Kinase 2 and the SCF(β-TRCP) Ubiquitin Ligase in Hippocampal Neurons
por: Ang, Xiaolu L., et al.
Publicado: (2008)

Regulation of Interleukin-10 Receptor Ubiquitination and Stability by Beta-TrCP-Containing Ubiquitin E3 Ligase
por: Jiang, Hui, et al.
Publicado: (2011)

SCF(Fbxl3) Ubiquitin Ligase Targets Cryptochromes at Their Cofactor Pocket
por: Xing, Weiman, et al.
Publicado: (2013)

The SCF(FBW7) ubiquitin ligase complex as a tumor suppressor in T cell leukemia
por: Thompson, Benjamin J., et al.
Publicado: (2007)

DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction
por: Wang, Zhiwei, et al.
Publicado: (2012)

The role of SCF ubiquitin-ligase complex at the beginning of life
por: Xie, Jiayan, et al.
Publicado: (2019)

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes
por: Baek, Kheewoong, et al.
Publicado: (2023)

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes
por: Baek, Kheewoong, et al.
Publicado: (2023)

The Importance of Ubiquitin E3 Ligases, SCF and APC/C, in Human Cancers
por: BOCHIS, OVIDIU VASILE, et al.
Publicado: (2015)

E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP
por: Bist, Pradeep, et al.
Publicado: (2017)

Chemical genetics of TOR identifies an SCF family E3 ubiquitin ligase inhibitor
por: Aghajanyy, Mariam, et al.
Publicado: (2010)

Hijacking of the Host SCF Ubiquitin Ligase Machinery by Plant Pathogens
por: Magori, Shimpei, et al.
Publicado: (2011)

Oskar Is Targeted for Degradation by the Sequential Action of Par-1, GSK-3, and the SCF(-Slimb) Ubiquitin Ligase
por: Morais-de-Sá, Eurico, et al.
Publicado: (2013)

Erratum: E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP
por: Bist, Pradeep, et al.
Publicado: (2017)

The Centrosomal E3 Ubiquitin Ligase FBXO31-SCF Regulates Neuronal Morphogenesis and Migration
por: Vadhvani, Mayur, et al.
Publicado: (2013)

A Hypoxia-Induced SCF(FBXL1) E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis
por: Zeng, Jun, et al.
Publicado: (2022)

GSK3-β Stimulates Claspin Degradation via β-TrCP Ubiquitin Ligase and Alters Cancer Cell Survival
por: Cabrera, Elisa, et al.
Publicado: (2019)

The E3 ubiquitin ligase ZNRF2 is a substrate of mTORC1 and regulates its activation by amino acids
por: Hoxhaj, Gerta, et al.
Publicado: (2016)

The SCF(Dia2) Ubiquitin E3 Ligase Ubiquitylates Sir4 and Functions in Transcriptional Silencing
por: Burgess, Rebecca J., et al.
Publicado: (2012)

NADPH oxidases promote apoptosis by activating ZNRF1 ubiquitin ligase in neurons treated with an exogenously applied oxidant
por: Wakatsuki, Shuji, et al.
Publicado: (2016)

Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1β(MYPT1) phosphatase complex and the SCF(βTrCP) E3 ubiquitin ligase
por: Banerjee, Sourav, et al.
Publicado: (2014)

SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination
por: Guan, Yongjuan, et al.
Publicado: (2022)

An integrative pan-cancer analysis revealing the difference in small ring finger family of SCF E3 ubiquitin ligases
por: Huang, Tingting, et al.
Publicado: (2022)

Wrenches in the works: drug discovery targeting the SCF ubiquitin ligase and APC/C complexes
por: Cardozo, Timothy, et al.
Publicado: (2007)

SCF(Cdc4) ubiquitin ligase regulates synaptonemal complex formation during meiosis
por: Zhu, Zhihui, et al.
Publicado: (2020)

KF-1 Ubiquitin Ligase: An Anxiety Suppressor
por: Hashimoto-Gotoh, Tamotsu, et al.
Publicado: (2009)

The Acidic Tail of the Cdc34 Ubiquitin-conjugating Enzyme Functions in Both Binding to and Catalysis with Ubiquitin Ligase SCF(Cdc4)
por: Kleiger, Gary, et al.
Publicado: (2009)

SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway
por: Liu, Jia, et al.
Publicado: (2014)

SCF(Slimb) ubiquitin ligase suppresses condensin II–mediated nuclear reorganization by degrading Cap-H2
por: Buster, Daniel W., et al.
Publicado: (2013)

Inhibition of FOXO3 Tumor Suppressor Function by βTrCP1 through Ubiquitin-Mediated Degradation in a Tumor Mouse Model
por: Tsai, Wen-Bin, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_2inm7bs0clge9rjiru95co4v4h