Nuclear lamina dysfunction triggers a germline stem cell checkpoint

LEM domain (LEM-D) proteins are conserved components of the nuclear lamina (NL) that contribute to stem cell maintenance through poorly understood mechanisms. The Drosophila emerin homolog Otefin (Ote) is required for maintenance of germline stem cells (GSCs) and gametogenesis. Here, we show that ot...

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Detalles Bibliográficos
Autores principales: Barton, Lacy J., Duan, Tingting, Ke, Wenfan, Luttinger, Amy, Lovander, Kaylee E., Soshnev, Alexey A., Geyer, Pamela K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160405/
https://www.ncbi.nlm.nih.gov/pubmed/30262885
http://dx.doi.org/10.1038/s41467-018-06277-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160405/
https://www.ncbi.nlm.nih.gov/pubmed/30262885
http://dx.doi.org/10.1038/s41467-018-06277-z

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