High-resolution NMR studies of antibiotics in cellular membranes

The alarming rise of antimicrobial resistance requires antibiotics with unexploited mechanisms. Ideal templates could be antibiotics that target the peptidoglycan precursor lipid II, known as the bacterial Achilles heel, at an irreplaceable pyrophosphate group. Such antibiotics would kill multidrug-...

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Detalles Bibliográficos
Autores principales: Medeiros-Silva, João, Jekhmane, Shehrazade, Paioni, Alessandra Lucini, Gawarecka, Katarzyna, Baldus, Marc, Swiezewska, Ewa, Breukink, Eefjan, Weingarth, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160437/
https://www.ncbi.nlm.nih.gov/pubmed/30262913
http://dx.doi.org/10.1038/s41467-018-06314-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160437/
https://www.ncbi.nlm.nih.gov/pubmed/30262913
http://dx.doi.org/10.1038/s41467-018-06314-x

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