Crown ethers reverse P-glycoprotein-mediated multidrug resistance in cancer cells

Multidrug resistance (MDR) is a widespread phenomenon exhibited by many cancers and represents a fundamental obstacle for successful cancer treatments. Tumour cells commonly achieve MDR phenotype through overexpression and/or increased activity of ABC transporters. P-glycoprotein transporter (P-gp,...

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Detalles Bibliográficos
Autores principales: Guberović, Iva, Marjanović, Marko, Mioč, Marija, Ester, Katja, Martin-Kleiner, Irena, Šumanovac Ramljak, Tatjana, Mlinarić-Majerski, Kata, Kralj, Marijeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160470/
https://www.ncbi.nlm.nih.gov/pubmed/30262858
http://dx.doi.org/10.1038/s41598-018-32770-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160470/
https://www.ncbi.nlm.nih.gov/pubmed/30262858
http://dx.doi.org/10.1038/s41598-018-32770-y

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