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Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells

Innate lymphoid cells (ILCs) play critical roles in mucosal barrier defense and tissue homeostasis. While ILCs are depleted in HIV-1 infection, this phenomenon is not a generalized feature of all viral infections. Here we show in untreated SIV-infected rhesus macaques (RMs) that ILC3s are lost rapid...

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Detalles Bibliográficos
Autores principales: Mudd, Joseph C., Busman-Sahay, Kathleen, DiNapoli, Sarah R., Lai, Stephen, Sheik, Virginia, Lisco, Andrea, Deleage, Claire, Richardson, Brian, Palesch, David J., Paiardini, Mirko, Cameron, Mark, Sereti, Irini, Reeves, R. Keith, Estes, Jacob D., Brenchley, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160474/
https://www.ncbi.nlm.nih.gov/pubmed/30262807
http://dx.doi.org/10.1038/s41467-018-05528-3