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Leptin Elicits LTC(4) Synthesis by Eosinophils Mediated by Sequential Two-Step Autocrine Activation of CCR3 and PGD(2) Receptors

Leptin is a cytokine, produced mainly by mature adipocytes, that regulates the central nervous system, mainly to suppress appetite and stimulate energy expenditure. Leptin also regulates the immune response by controlling activation of immunomodulatory cells, including eosinophils. While emerging as...

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Detalles Bibliográficos
Autores principales: Amorim, Natália R. T., Luna-Gomes, Tatiana, Gama-Almeida, Marcos, Souza-Almeida, Glaucia, Canetti, Claudio, Diaz, Bruno L., Weller, Peter F., Torres Bozza, Patricia, Maya-Monteiro, Clarissa M., Bandeira-Melo, Christianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160734/
https://www.ncbi.nlm.nih.gov/pubmed/30298073
http://dx.doi.org/10.3389/fimmu.2018.02139