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Leptin Elicits LTC(4) Synthesis by Eosinophils Mediated by Sequential Two-Step Autocrine Activation of CCR3 and PGD(2) Receptors
Leptin is a cytokine, produced mainly by mature adipocytes, that regulates the central nervous system, mainly to suppress appetite and stimulate energy expenditure. Leptin also regulates the immune response by controlling activation of immunomodulatory cells, including eosinophils. While emerging as...
Autores principales: | Amorim, Natália R. T., Luna-Gomes, Tatiana, Gama-Almeida, Marcos, Souza-Almeida, Glaucia, Canetti, Claudio, Diaz, Bruno L., Weller, Peter F., Torres Bozza, Patricia, Maya-Monteiro, Clarissa M., Bandeira-Melo, Christianne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160734/ https://www.ncbi.nlm.nih.gov/pubmed/30298073 http://dx.doi.org/10.3389/fimmu.2018.02139 |
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