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ATP-activated decrosslinking and charge-reversal vectors for siRNA delivery and cancer therapy

Stimuli-responsive polycations have been developed for improved nucleic acid transfection and enhanced therapeutic efficacy. The most reported mechanisms for controlled release of siRNA are based on polyelectrolyte exchange reactions in the cytoplasm and the degradation of polycations initiated by s...

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Detalles Bibliográficos
Autores principales:	Zhou, Zhanwei, Zhang, Qingyan, Zhang, Minghua, Li, Huipeng, Chen, Gang, Qian, Chenggen, Oupicky, David, Sun, Minjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160761/ https://www.ncbi.nlm.nih.gov/pubmed/30279726 http://dx.doi.org/10.7150/thno.26889

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