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Detection of Felis catus papillomavirus type 2 within multicentric basosquamous carcinoma in a domestic cat

A 12-year-old neutered male domestic shorthair cat was presented with a 3-year history of multiple nonpruritic, ulcerated, plaque-like skin lesions but no other clinical signs. A systemic examination revealed mild lymphadenopathy. Histopathologic analysis of the skin lesions revealed multicentric ba...

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Detalles Bibliográficos
Autores principales: OH, Ye-In, CHEON, Doo-Sung, LEE, Jung-Keun, CHOI, Mi-Hyun, HWANG, Sun-Young, KIM, Hyun-Wook, KANG, Byung-Jae, YOUN, Hwa-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160893/
https://www.ncbi.nlm.nih.gov/pubmed/29998924
http://dx.doi.org/10.1292/jvms.17-0702
Descripción
Sumario:A 12-year-old neutered male domestic shorthair cat was presented with a 3-year history of multiple nonpruritic, ulcerated, plaque-like skin lesions but no other clinical signs. A systemic examination revealed mild lymphadenopathy. Histopathologic analysis of the skin lesions revealed multicentric basosquamous carcinoma (BSC). Immunohistochemical analysis, PCR, and sequencing detected Felis catus papillomavirus type 2 (FcaPV-2) within the tumors. As BSC is rare in cats, clinical behavior has not been established. To our knowledge, this is the first case report to demonstrate detection of FcaPV-2 within a BSC in a domestic cat.