Processing Impact on Performance of Solid Dispersions

The development of a weakly basic compound is often challenging due to changes in pH that the drug experiences throughout the gastrointestinal tract. As the drug transitions from the low pH of the stomach to the higher pH of the small intestine, drug solubility decreases. A stomach with a higher pH,...

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Detalles Bibliográficos
Autores principales: Zhang, Dan, Lee, Yung-Chi, Shabani, Zaher, Frankenfeld Lamm, Celeste, Zhu, Wei, Li, Yongjun, Templeton, Allen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160931/
https://www.ncbi.nlm.nih.gov/pubmed/30200245
http://dx.doi.org/10.3390/pharmaceutics10030142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160931/
https://www.ncbi.nlm.nih.gov/pubmed/30200245
http://dx.doi.org/10.3390/pharmaceutics10030142

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