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Pharmacokinetics and Anti-Gastric Ulceration Activity of Oral Administration of Aceclofenac and Esomeprazole in Rats

This study examined the effects of esomeprazole on aceclofenac pharmacokinetics and gastrointestinal complications in rats. Aceclofenac alone, or in combination with esomeprazole, was orally administered to male Sprague-Dawley rats. Plasma concentrations of aceclofenac, its major metabolite diclofen...

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Detalles Bibliográficos
Autores principales:	Kim, Tae Hwan, Thapa, Subindra Kazi, Lee, Da Young, Chung, Seung Eun, Lim, Jun Young, Jeong, Hyeon Myeong, Song, Chang Ho, Choi, Youn-Woong, Cho, Sang-Min, Nam, Kyu-Yeol, Kang, Won-Ho, Shin, Soyoung, Shin, Beom Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160962/ https://www.ncbi.nlm.nih.gov/pubmed/30200587 http://dx.doi.org/10.3390/pharmaceutics10030152

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