Synthesis, Structure–Activity Relationships and In Vitro Toxicity Profile of Lactose-Based Fatty Acid Monoesters as Possible Drug Permeability Enhancers

Permeability enhancers are receiving increased attention arising from their ability to increase transepithelial permeability and thus, bioavailability of orally or pulmonary administered biopharmaceutics. Here we present the synthesis and the in vitro assaying of a series of lactose-based non-ionic...

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Detalles Bibliográficos
Autores principales: Lucarini, Simone, Fagioli, Laura, Cavanagh, Robert, Liang, Wanling, Perinelli, Diego Romano, Campana, Mario, Stolnik, Snjezana, Lam, Jenny K. W., Casettari, Luca, Duranti, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161018/
https://www.ncbi.nlm.nih.gov/pubmed/29970849
http://dx.doi.org/10.3390/pharmaceutics10030081

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