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Iron in Friedreich Ataxia: A Central Role in the Pathophysiology or an Epiphenomenon?
Friedreich ataxia is a neurodegenerative disease with an autosomal recessive inheritance. In most patients, the disease is caused by the presence of trinucleotide GAA expansions in the first intron of the frataxin gene. These expansions cause the decreased expression of this mitochondrial protein. M...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161073/ https://www.ncbi.nlm.nih.gov/pubmed/30235822 http://dx.doi.org/10.3390/ph11030089 |