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Ketamine and Ceftriaxone-Induced Alterations in Glutamate Levels Do Not Impact the Specific Binding of Metabotropic Glutamate Receptor Subtype 5 Radioligand [(18)F]PSS232 in the Rat Brain

Several studies showed that [(11)C]ABP688 binding is altered following drug-induced perturbation of glutamate levels in brains of humans, non-human primates and rats. We evaluated whether the fluorinated derivative [(18)F]PSS232 can be used to assess metabotropic glutamate receptor 5 (mGluR5) availa...

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Detalles Bibliográficos
Autores principales:	Müller Herde, Adrienne, Boss, Silvan D., He, Yingfang, Schibli, Roger, Mu, Linjing, Ametamey, Simon M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161118/ https://www.ncbi.nlm.nih.gov/pubmed/30158438 http://dx.doi.org/10.3390/ph11030083

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