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Stimuli Responsive Polymeric Systems for Cancer Therapy
Nanoscale polymers systems have dominated the revolution of drug delivery advancement. Their potential in the fight against cancer is unrivalled with other technologies. Their functionality increase, targeting ability and stimuli responsive nature have led to a major boom in research focus. This rev...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161138/ https://www.ncbi.nlm.nih.gov/pubmed/30131473 http://dx.doi.org/10.3390/pharmaceutics10030136 |
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author | Alsuraifi, Ali Curtis, Anthony Lamprou, Dimitrios A. Hoskins, Clare |
author_facet | Alsuraifi, Ali Curtis, Anthony Lamprou, Dimitrios A. Hoskins, Clare |
author_sort | Alsuraifi, Ali |
collection | PubMed |
description | Nanoscale polymers systems have dominated the revolution of drug delivery advancement. Their potential in the fight against cancer is unrivalled with other technologies. Their functionality increase, targeting ability and stimuli responsive nature have led to a major boom in research focus. This review article concentrates on the use of these smart polymers in cancer therapy. Nanotechnologies have shown potential as drug carriers leading to increased drug efficacy and penetration. Multifunctional smart carriers which can release their payload upon an external or internal trigger such as pH or temperature are proving to be major frontrunners in the development of effective strategies to overcome this disease with minimal patient side effects. |
format | Online Article Text |
id | pubmed-6161138 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61611382018-10-01 Stimuli Responsive Polymeric Systems for Cancer Therapy Alsuraifi, Ali Curtis, Anthony Lamprou, Dimitrios A. Hoskins, Clare Pharmaceutics Review Nanoscale polymers systems have dominated the revolution of drug delivery advancement. Their potential in the fight against cancer is unrivalled with other technologies. Their functionality increase, targeting ability and stimuli responsive nature have led to a major boom in research focus. This review article concentrates on the use of these smart polymers in cancer therapy. Nanotechnologies have shown potential as drug carriers leading to increased drug efficacy and penetration. Multifunctional smart carriers which can release their payload upon an external or internal trigger such as pH or temperature are proving to be major frontrunners in the development of effective strategies to overcome this disease with minimal patient side effects. MDPI 2018-08-22 /pmc/articles/PMC6161138/ /pubmed/30131473 http://dx.doi.org/10.3390/pharmaceutics10030136 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Alsuraifi, Ali Curtis, Anthony Lamprou, Dimitrios A. Hoskins, Clare Stimuli Responsive Polymeric Systems for Cancer Therapy |
title | Stimuli Responsive Polymeric Systems for Cancer Therapy |
title_full | Stimuli Responsive Polymeric Systems for Cancer Therapy |
title_fullStr | Stimuli Responsive Polymeric Systems for Cancer Therapy |
title_full_unstemmed | Stimuli Responsive Polymeric Systems for Cancer Therapy |
title_short | Stimuli Responsive Polymeric Systems for Cancer Therapy |
title_sort | stimuli responsive polymeric systems for cancer therapy |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161138/ https://www.ncbi.nlm.nih.gov/pubmed/30131473 http://dx.doi.org/10.3390/pharmaceutics10030136 |
work_keys_str_mv | AT alsuraifiali stimuliresponsivepolymericsystemsforcancertherapy AT curtisanthony stimuliresponsivepolymericsystemsforcancertherapy AT lamproudimitriosa stimuliresponsivepolymericsystemsforcancertherapy AT hoskinsclare stimuliresponsivepolymericsystemsforcancertherapy |