Co-Amorphous Screening for the Solubility Enhancement of Poorly Water-Soluble Mirabegron and Investigation of Their Intermolecular Interactions and Dissolution Behaviors

In the present study, the screening of Mirabegron (MBR) co-amorphous was performed to produce water-soluble and thermodynamically stable MBR co-amorphous with the purpose of overcoming the water solubility problem of MBR. MBR is Biopharmaceutics Classification System (BCS) class II drug used for the...

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Detalles Bibliográficos
Autores principales: An, Ji-Hun, Lim, Changjin, Kiyonga, Alice Nguvoko, Chung, In Hwa, Lee, In Kyu, Mo, Kilwoong, Park, Minho, Youn, Wonno, Choi, Won Rak, Suh, Young-Ger, Jung, Kiwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161252/
https://www.ncbi.nlm.nih.gov/pubmed/30189645
http://dx.doi.org/10.3390/pharmaceutics10030149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161252/
https://www.ncbi.nlm.nih.gov/pubmed/30189645
http://dx.doi.org/10.3390/pharmaceutics10030149

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