Antenatal sildenafil administration to prevent pulmonary hypertension in congenital diaphragmatic hernia (SToP-PH): study protocol for a phase I/IIb placenta transfer and safety study

BACKGROUND: Congenital diaphragmatic hernia is an orphan disease with high neonatal mortality and significant morbidity. An important cause for this is pulmonary hypertension, for which no effective postnatal therapy is available to date. An innovative strategy aiming at treating or preventing pulmo...

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Detalles Bibliográficos
Autores principales: Russo, Francesca Maria, Benachi, Alexandra, Van Mieghem, Tim, De Hoon, Jan, Van Calsteren, Kristel, Annaert, Pieter, Tréluyer, Jean-Marc, Allegaert, Karel, Deprest, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161420/
https://www.ncbi.nlm.nih.gov/pubmed/30261903
http://dx.doi.org/10.1186/s13063-018-2897-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161420/
https://www.ncbi.nlm.nih.gov/pubmed/30261903
http://dx.doi.org/10.1186/s13063-018-2897-8

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