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Manipulating plant RNA-silencing pathways to improve the gene editing efficiency of CRISPR/Cas9 systems

BACKGROUND: The CRISPR/Cas9 system, composed of a single-guide RNA for target recognition and a Cas9 protein for DNA cleavage, has the potential to revolutionize agriculture as well as medicine. Even though extensive work has been done to improve the gene editing activity of CRISPR/Cas9, little is k...

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Detalles Bibliográficos
Autores principales:	Mao, Yanfei, Yang, Xiaoxuan, Zhou, Yiting, Zhang, Zhengjing, Botella, Jose Ramon, Zhu, Jian-Kang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161460/ https://www.ncbi.nlm.nih.gov/pubmed/30266091 http://dx.doi.org/10.1186/s13059-018-1529-7

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