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Ingenol mebutate induces a tumor cell-directed inflammatory response and antimicrobial peptides thereby promoting rapid tumor destruction and wound healing

BACKGROUND: Ingenol mebutat (IM)-gel is effective for the topical treatment of epithelial tumors, including actinic keratoses (AKs) or anogenital warts (AGW). AK patients treated with IM develop intensified inflammatory reactions on sights of prior clinical visible or palpable AKs as compared to the...

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Detalles Bibliográficos
Autores principales:	Braun, Stephan Alexander, Baran, Julia, Schrumpf, Holger, Buhren, Bettina Alexandra, Bölke, Edwin, Homey, Bernhard, Gerber, Peter Arne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161468/ https://www.ncbi.nlm.nih.gov/pubmed/30266096 http://dx.doi.org/10.1186/s40001-018-0343-8

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