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Microfluidic pumping using artificial magnetic cilia
One of the vital functions of naturally occurring cilia is fluid transport. Biological cilia use spatially asymmetric strokes to generate a net fluid flow that can be utilized for feeding, swimming, and other functions. Biomimetic synthetic cilia with similar asymmetric beating can be useful for flu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161502/ https://www.ncbi.nlm.nih.gov/pubmed/31057899 http://dx.doi.org/10.1038/s41378-018-0010-9 |
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author | Hanasoge, Srinivas Hesketh, Peter J. Alexeev, Alexander |
author_facet | Hanasoge, Srinivas Hesketh, Peter J. Alexeev, Alexander |
author_sort | Hanasoge, Srinivas |
collection | PubMed |
description | One of the vital functions of naturally occurring cilia is fluid transport. Biological cilia use spatially asymmetric strokes to generate a net fluid flow that can be utilized for feeding, swimming, and other functions. Biomimetic synthetic cilia with similar asymmetric beating can be useful for fluid manipulations in lab-on-chip devices. In this paper, we demonstrate the microfluidic pumping by magnetically actuated synthetic cilia arranged in multi-row arrays. We use a microchannel loop to visualize flow created by the ciliary array and to examine pumping for a range of cilia and microchannel parameters. We show that magnetic cilia can achieve flow rates of up to 11 μl/min with the pressure drop of ~1 Pa. Such magnetic ciliary array can be useful in microfluidic applications requiring rapid and controlled fluid transport. |
format | Online Article Text |
id | pubmed-6161502 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-61615022019-05-03 Microfluidic pumping using artificial magnetic cilia Hanasoge, Srinivas Hesketh, Peter J. Alexeev, Alexander Microsyst Nanoeng Article One of the vital functions of naturally occurring cilia is fluid transport. Biological cilia use spatially asymmetric strokes to generate a net fluid flow that can be utilized for feeding, swimming, and other functions. Biomimetic synthetic cilia with similar asymmetric beating can be useful for fluid manipulations in lab-on-chip devices. In this paper, we demonstrate the microfluidic pumping by magnetically actuated synthetic cilia arranged in multi-row arrays. We use a microchannel loop to visualize flow created by the ciliary array and to examine pumping for a range of cilia and microchannel parameters. We show that magnetic cilia can achieve flow rates of up to 11 μl/min with the pressure drop of ~1 Pa. Such magnetic ciliary array can be useful in microfluidic applications requiring rapid and controlled fluid transport. Nature Publishing Group UK 2018-06-04 /pmc/articles/PMC6161502/ /pubmed/31057899 http://dx.doi.org/10.1038/s41378-018-0010-9 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Hanasoge, Srinivas Hesketh, Peter J. Alexeev, Alexander Microfluidic pumping using artificial magnetic cilia |
title | Microfluidic pumping using artificial magnetic cilia |
title_full | Microfluidic pumping using artificial magnetic cilia |
title_fullStr | Microfluidic pumping using artificial magnetic cilia |
title_full_unstemmed | Microfluidic pumping using artificial magnetic cilia |
title_short | Microfluidic pumping using artificial magnetic cilia |
title_sort | microfluidic pumping using artificial magnetic cilia |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161502/ https://www.ncbi.nlm.nih.gov/pubmed/31057899 http://dx.doi.org/10.1038/s41378-018-0010-9 |
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