Diagnostic and Prognostic Role of Neutrophil-to-Lymphocyte Ratio in Early and Late Phase of Sepsis

OBJECTIVE: Early diagnosis of sepsis is necessary to decrease morbidity and mortality. This study aims to evaluate neutrophil-to-lymphocyte ratio (NLR) as diagnostic and prognostic of early and late phase of sepsis. METHODS: It was a prospective, observational study, conducted in Intensive Care and...

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Autores principales: Kaushik, Rajnish, Gupta, Monika, Sharma, Madhu, Jash, Debraj, Jain, Neetu, Sinha, Nitin, Chaudhry, Aditya, Chaudhry, Dhruva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161585/
https://www.ncbi.nlm.nih.gov/pubmed/30294133
http://dx.doi.org/10.4103/ijccm.IJCCM_59_18
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author Kaushik, Rajnish
Gupta, Monika
Sharma, Madhu
Jash, Debraj
Jain, Neetu
Sinha, Nitin
Chaudhry, Aditya
Chaudhry, Dhruva
author_facet Kaushik, Rajnish
Gupta, Monika
Sharma, Madhu
Jash, Debraj
Jain, Neetu
Sinha, Nitin
Chaudhry, Aditya
Chaudhry, Dhruva
author_sort Kaushik, Rajnish
collection PubMed
description OBJECTIVE: Early diagnosis of sepsis is necessary to decrease morbidity and mortality. This study aims to evaluate neutrophil-to-lymphocyte ratio (NLR) as diagnostic and prognostic of early and late phase of sepsis. METHODS: It was a prospective, observational study, conducted in Intensive Care and High Dependency Unit (Daycare) of the Department of Pulmonary and Critical Care Medicine (tertiary care center), Rohtak, from January 2017 to December 2017. A total of 56 cases of newly diagnosed cases of sepsis were included in the study and 20 healthy adults were taken as controls. Daily NLR was calculated in cases till the primary outcome. RESULTS: The results suggested that NLR seems to have promising role as diagnostic and prognostic marker (with P = 0.001 and P = 0.045, respectively) in sepsis. CONCLUSION: The study suggests that NLR can be a useful diagnostic and prognostic marker in sepsis.
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spelling pubmed-61615852018-10-05 Diagnostic and Prognostic Role of Neutrophil-to-Lymphocyte Ratio in Early and Late Phase of Sepsis Kaushik, Rajnish Gupta, Monika Sharma, Madhu Jash, Debraj Jain, Neetu Sinha, Nitin Chaudhry, Aditya Chaudhry, Dhruva Indian J Crit Care Med Brief Communication OBJECTIVE: Early diagnosis of sepsis is necessary to decrease morbidity and mortality. This study aims to evaluate neutrophil-to-lymphocyte ratio (NLR) as diagnostic and prognostic of early and late phase of sepsis. METHODS: It was a prospective, observational study, conducted in Intensive Care and High Dependency Unit (Daycare) of the Department of Pulmonary and Critical Care Medicine (tertiary care center), Rohtak, from January 2017 to December 2017. A total of 56 cases of newly diagnosed cases of sepsis were included in the study and 20 healthy adults were taken as controls. Daily NLR was calculated in cases till the primary outcome. RESULTS: The results suggested that NLR seems to have promising role as diagnostic and prognostic marker (with P = 0.001 and P = 0.045, respectively) in sepsis. CONCLUSION: The study suggests that NLR can be a useful diagnostic and prognostic marker in sepsis. Medknow Publications & Media Pvt Ltd 2018-09 /pmc/articles/PMC6161585/ /pubmed/30294133 http://dx.doi.org/10.4103/ijccm.IJCCM_59_18 Text en Copyright: © 2018 Indian Journal of Critical Care Medicine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Brief Communication
Kaushik, Rajnish
Gupta, Monika
Sharma, Madhu
Jash, Debraj
Jain, Neetu
Sinha, Nitin
Chaudhry, Aditya
Chaudhry, Dhruva
Diagnostic and Prognostic Role of Neutrophil-to-Lymphocyte Ratio in Early and Late Phase of Sepsis
title Diagnostic and Prognostic Role of Neutrophil-to-Lymphocyte Ratio in Early and Late Phase of Sepsis
title_full Diagnostic and Prognostic Role of Neutrophil-to-Lymphocyte Ratio in Early and Late Phase of Sepsis
title_fullStr Diagnostic and Prognostic Role of Neutrophil-to-Lymphocyte Ratio in Early and Late Phase of Sepsis
title_full_unstemmed Diagnostic and Prognostic Role of Neutrophil-to-Lymphocyte Ratio in Early and Late Phase of Sepsis
title_short Diagnostic and Prognostic Role of Neutrophil-to-Lymphocyte Ratio in Early and Late Phase of Sepsis
title_sort diagnostic and prognostic role of neutrophil-to-lymphocyte ratio in early and late phase of sepsis
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161585/
https://www.ncbi.nlm.nih.gov/pubmed/30294133
http://dx.doi.org/10.4103/ijccm.IJCCM_59_18
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